New Alzheimer’s Drug Shows Promise for Those with the Disease

By David Parks, 9:00 am on

Alzheimer’s patients experience symptoms secondary to the interruption of neuron communication and cellular damage that occurs when plaques accumulate in the brain. However, researchers from the Biogen laboratory in Cambridge, Massachusetts, have recently developed a medication that counteracts the condition and is bringing hope to seniors and their Fort Worth Alzheimer’s care providers. 

Alzheimer’s Development

Plaque formation is typically a natural part of the aging process. Under normal conditions, specialized proteins prevent an abundance by eliminating the plaques as they form. For unknown reasons, these chemical compounds lose their ability to clean the brain effectively, which results in the destructive conglomeration. The newly developed medication called aducanumab removes these plaques even after they form. 

Clinical Trials

After developing the formulation, researchers performed clinical trials on laboratory mice. During the study, the drug successfully passed the blood-brain barrier, and confronted and removed cerebral plaques. Human trials began shortly thereafter. 

The scientists gathered 165 patients diagnosed as being in the early stages of Alzheimer’s. The volunteers were divided into five groups. Four received varying doses of the medication, and one group received a placebo. Medication administrations occurred via an intravenous infusion each month for one year. Of the entire group, 125 completed the course of treatment. The remaining participants quit the study due to side effects, which included fluid build-up in the brain. 

PET scan evaluations revealed that the participants receiving the aducanumab had an increasing amount of plaque reduction over time. The brains of the group taking the highest dose of medication showed the greatest effects. 

Inconclusive Results

Trials will continue on larger groups of Alzheimer’s patients for the next four or five years. While the medication shows promising results, neuropsychologists claim that not enough is known concerning whether the treatment will improve cognitive function. Early studies did not address cognitive issues. The scientists also warn that previously introduced medications initially seemed promising only to fail in the long run.

As researchers continue to work on an effective treatment for Alzheimer’s, families can turn to Home Care Assistance of Fort Worth. We are the leading provider of Fort Worth, TX, at-home care local families trust to help seniors with cognitive disorders age in place with dignity. Call (817) 349-7599 today to have a friendly Care Manager answer your questions and customize a care plan for your loved one.

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